AI + MULTI-OMICS  ➡  PRECISION ONCOLOGY

The Chiu Lab is an interdisciplinary team affiliate with the UPMC Hillman Cancer Center and Department of Medicine at the University of Pittsburgh. Our mission is to bridge cutting-edge computational algorithms to unmet needs in precision oncology. Read more about the PI.

Research highlights

Extending in vitro CRISPR screens to in vivo applications 

Our latest Science Advances paper presents a novel “transfer learning” scheme that integrates cancer multi-omics and extends in vitro genetic screens to impracticable-to-screen tumors. The study was highlighted by @NCIgenomics as the #1 paper of 2021. Read the article.

AI-based in silico drug screening 

Accurate prediction of cancer cells’ response to treatments is a key towards precision oncology. We developed an innovative, accurate AI model that virtually screens for ~300 anti-cancer drugs. Our study was selected as Springer Nature Research Highlights in Genetics of 2019 and has been cited for 150+ times within two years. Read the article.

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Our lab is located at The Assembly – where history, innovation, technology, and medicine meet!